HANGZHOU BIO-BOUNCE TECHNOLOGY CO.,LTD

Peptide Synthesis

SPPS+LPPS combination

Peptide synthesis is mainly achieved by two methods: Solid-Phase Peptide Synthesis (SPPS) and Liquid-Phase Peptide Synthesis (LPPS).

Solid-Phase Peptide Synthesis (SPPS) uses resin as a solid-phase carrier, and amino acids are gradually added to the resin to extend the peptide chain through deprotection and coupling cycles.

The advantages are high synthesis efficiency, high purity, and suitability for mass production.

However, longer peptide sequences may lead to lower yields.

On the other hand, liquid phase synthesis (LPPS) carries out the gradual coupling and deprotection of amino acids in solution, which is suitable for the synthesis of shorter peptides and easy to be chemically modified, but the operation is complicated and the purification process is more cumbersome.

We use SPPS+LPPS combination technology to obtain cost-effectivness production.

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